A TATA box is a DNA sequence (''cis''-element) found in the promoter region of most genes (it is considered to be a promoter sequence). It is the binding site of either transcription factors or histones (binding of one blocks binding of the other). It has the DNA sequence 5' TATAAA(A/G) 3'. In eukaryotes, it is normally bound by the TATA-binding protein (TBP), which melts the DNA, and bends it through 90°. The AT-rich sequence facilitates easy melting. The TBP is an unusual protein in that it binds the minor groove and binds with a beta sheet. Many genes lack a TATA box and use an initiator element or downstream core promoter instead. ==Location== Found in the promoter region of most genes, about 25 base pairs upstream from the start site of transcription. It is usually adjacent to GC rich sequences. ==Binding of histones== The binding of histones involves the N-terminal tail of H4. Gene expression
Why "box"? User:DragonflySixtyseven 20:10, 12 Jan 2005 (UTC) :It might be because when you see TATA labelled in a sequence, you see a box around it. But that would just be a guess. :-P --User:G3pro 01:58, 13 Jan 2005 (UTC)
See other meanings of words starting from letter:
Words begining with TATA_box:
TATA_box
TATA_box
TATA box
A TATA box is a DNA sequence (''cis''-element) found in the promoter region of most genes (it is considered to be a promoter sequence). It is the binding site of either transcription factors or histones (binding of one blocks binding of the other). It has the DNA sequence 5' TATAAA(A/G) 3'. In eukaryotes, it is normally bound by the TATA-binding protein (TBP), which melts the DNA, and bends it through 90°. The AT-rich sequence facilitates easy melting. The TBP is an unusual protein in that it binds the minor groove and binds with a beta sheet. Many genes lack a TATA box and use an initiator element or downstream core promoter instead. ==Location== Found in the promoter region of most genes, about 25 base pairs upstream from the start site of transcription. It is usually adjacent to GC rich sequences. ==Binding of histones== The binding of histones involves the N-terminal tail of H4. Gene expression
TATA box
Why "box"? User:DragonflySixtyseven 20:10, 12 Jan 2005 (UTC) :It might be because when you see TATA labelled in a sequence, you see a box around it. But that would just be a guess. :-P --User:G3pro 01:58, 13 Jan 2005 (UTC)
See other meanings of words starting from letter:
T
TA | TB | TC | TD | TE | TF | TG | TH | TI | TJ | TK | TL | TŁ | TM | TN | TO | TP | TR | TS | TU | TW | TX | TY | TZ |Words begining with TATA_box:
TATA_box
TATA_box
These materials are based on Wikipedia and licensed under the GNU FDL
YouTube.com videos better site than Turbo Tax 2007
