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IschemiaIn medicine, ischemia (Greek language ισχαιμία, ''isch-'' is ''restriction'', ''hema'' or ''haema'' is blood) is a ''restriction in blood supply'', generally due to factors in the blood vessels, with resultant damage or dysfunction of tissue. ==Mechanism== Rather than in hypoxia, a more general term denoting a shortage of oxygen, ''ischemia'' is an absolute or relative shortage of the blood supply to an organ. Relative shortage means the mismatch of blood supply (oxygen delivery) and blood request for adequate oxygenation of tissue. Ischemia can also be described as inadequate flow of blood to a part of the body, caused by constriction or blockage of the blood vessels supplying it. Ischemia of heart muscle produces angina pectoris.1 This can be due to: * atherosclerosis (lipid-laden placques obstructing the lumen of artery) * hypotension (low blood pressure, e.g. in sepsis, heart failure) * thromboembolism (blood clots) * outside compression of a blood vessel, e.g. by a tumor * foreign bodies in the circulation (e.g. amniotic fluid in amniotic fluid embolism) ==References== 1. Oxford Reference: Concise Medical Dictionary (1990, 3rd ed.). Oxford University Press: Market House Books. ==Consequences== As the carrier of oxygen (oxygen is mainly bound to hemoglobin) insufficient blood supply leads to hypoxic tissue (anoxic in case of no oxygen supply at all) with the consequence of necrosis which causes cell death. Ischemia is a feature of heart diseases, transient ischemic attacks, cerebrovascular accidents, and peripheral artery occlusive disease. ==See also== * Infarction Cardiology IschemiaLinks to cryonics are too obscure to belong in a very general article on ischemia. Links to ''organ preservation'' for transplantation purposes are more in touch with the subject than this. Also avoid dumping external links everywhere that only emphasise fringe statements. User:Jfdwolff | User_talk:Jfdwolff 08:47, 16 May 2004 ---- ==Hypoxia vs. Ischaemia== For a reduction in oxygen the term "hypoxia" is more often used and more accurate. Ischemia should be reserved for a reduction in blood supply. content of article: :''* inability of the tissues to extract oxygen from the blood (e.g. sepsis)'' There is no inability of tissue to extract oxygen, the ability of the tissue to "use" oxygen is dependent of vital cells ! Sepsis is a far more complicate life threatening syndrome than an "unability of extracting oxygen" or whatever the editor meant. ::''If insufficient oxygen is supplied to the tissue to maintain life in that tissue, the tissue dies, or infarcts.'' answer: Tissue never dies, it is the human being or animals that die but not tissues. Tissues can become hypoxic, anoxic, apoptotic or necrotic. User:149.148.181.110. :You can make these changes yourself, just press "edit" at the bottom! I have made some changes on the basis of your suggestions. User:Jfdwolff | User_talk:Jfdwolff 19:49, 16 Jun 2004 (UTC) See other meanings of words starting from letter: IIA | IB | IC | ID | IE | IF | IG | IH | IJ | IK | IL | IM | IN | IO | IP | IR | IS | IT | IU | IW | IX | IY | IZ |Words begining with Ischemia: Ischemia Ischemia |
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