Gastroenteritis, or inflammation of the gastrointestinal tract, is an illness of fever, diarrhoea and/or vomiting caused by an infectious virus, bacterium or parasite. It usually is of acute onset, normally lasting less than 10 days and self-limiting. Sometimes it is referred to simply as 'gastro'. It is often refered to as the stomach flu even though it is not related to influenza. ==Aetiology== ===Viral causes=== The most common viral causes of acute gastroenteritis (AGE) in children <5 years of age in both developed nations as well as developing countries are rotavirus (up to 50% of the cases), noroviruses (the most common cause of outbreaks of AGE in all age groups), adenoviridae AD-40 and AD-41, astrovirus, and sapovirus. ===Bacterial causes=== This is less common in developed countries. ''Campylobacter jejuni'' is responsible for 5-10% of cases, whereas ''Salmonella'' species, ''Shigella'' species, and various pathogenic types of ''Escherichia coli'' account for a small percentage. In the third world enterotoxigenic, enteropathogenic and enteroinvasive ''Escherichia coli'' are important due to the sheer number of cases, whereas ''Shigella'' causes debilitating illness and has increasing resistance against cheap and readily available antibiotics. Cholera, caused by ''Vibrio cholerae'' is another important cause of acute diarrhoeal illness and subsequent death in the developing world. ===Parasites=== Outbreaks of ''Giardia lamblia'' can cause dehydrating diarrhoea in infants, and ''Cryptosporidium'' is known to cause 1-4% of cases of acute diarrhoea in hospitalised infants. ==Epidemiology== Globally, diarrhea caused 4.6 million deaths in children in 1980 alone, most of these in the third world. This number has now come down significantly to approximately 1.5 million deaths annually, largely due to global introduction of proper oral rehydration therapy (Victora et al 2000). The incidence in the developed nation is as high as 1-2.5 cases per child per year and a major cause of hospitalisation in this age group. ==Clinical features== The main symptoms include poor feeding in infants, vomiting and fever, usually rapidly followed by diarrhoea. Viral diarrhoea usually causes frequent watery stools, whereas blood stained diarrhoea may be indicative of bacterial colitis. The child with gastroenteritis may be lethargic and have signs of dehydration, dry mucous membranes, tachycardia, reduced skin turgor, sunken fontanelles and sunken eye balls, poor perfusion and ultimately shock. ==Differential diagnosis== It is important to consider infectious gastroenteritis as a diagnosis of exclusion. A few loose stools and vomiting may be the result of systemic infection such as pneumonia, septicaemia, urinary tract infection and even meningitis. Surgical conditions like appendicitis, intussusception and, rarely, even Hirschsprung's disease may mislead the clinician. ==Treatment== The main treatment of diarrhoeal illness in both children and adults is rehydration, i.e. replenishment of water lost in the stools. Depending on the degree of dehydration, this can be done orally with commercial or home-made rehydration fluids, or through vein delivery. ===Drug therapy=== Loperamide is an opioid analogue commonly used for symptomatic treatment of diarrhoea. It slows down gut motility, but does not cross the mature blood-brain barrier to cause the central nervous effect of other opioids. In too high doses, loperamide may cause constipation and significant slowing down of passage of faeces, but an appropriate single dose will not slow down the duration of the disease (Wingate et al, 2001). Loperamide is not recommended in children, especially in children younger than 2 years of age, as it may cause systemic toxicity due to an immature blood brain barrier, and oral rehydration therapy remains the main stay treatment for children. Antibiotics are of little or no use, unless persistent symptomatic colonisation (as seen in ''Giardia lamblia'' infestations) or septicaemia is present. ==Complications== Dehydration is the most concerning complication of the diarrhoea caused by gastroenteritis and needs prompt rectification by a clinician if severe. Febrile convulsions are not uncommon in children, especially with rotavirus infections. Sugar malabsorption is the most common complication, especially in infants. This may result in reappearance of diarrhoea once milk, and hence the sugar lactose, is reintroduced into the diet. ==References== Victora, C. G., Bryce, J., Fontaine, O., & Monasch, R. 2000, 'Reducing deaths from diarrhoea through oral rehydration therapy', ''Bulletin of The World Health Organization'', vol. 78, no. 10, pp. 1246-1255. Wingate D. et al. 2001. 'Guidelines for adults on self-medication for the treatment of acute diarrhoea', ''Alimentary Pharmacology & Therapeutics'', vol. 15, no. 6, pp. 773-782. ==External links== * [http://www.who.int/health_topics/diarrhoea/en/ The World Health Organisation on diarrhoea] * [http://www.emedicinehealth.com/articles/5962-1.asp eMedicine Health] Gastroenterology
IIRC: * the present gastroenteritis article describes infectious gastroenteritis, which is a class of diseases, but * gastroenteritis is a symptom (not a disease) whose causes can include ingestion of irritants like ethyl alcohol, aspirin, and cooking spices (and perhaps also overeating?). IMO someone willing to do more research than i am at the moment should confirm this, rename, and convert the redir to a Dab between infectious gastroenteritis and something else ( non-infectious gastroenteritis is probably ''not'' what we need).
--User:JerzyUser talk:Jerzy 06:33, 2005 Feb 24 (UTC)
See other meanings of words starting from letter:
Words begining with Gastroenteritis:
Gastroenteritis
Gastroenteritis
Gastroenteritis,_infectious
Gastroenteritis,_noninfectious,_unspec.
Gastroenteritis,_viral
Gastroenteritis
Gastroenteritis, or inflammation of the gastrointestinal tract, is an illness of fever, diarrhoea and/or vomiting caused by an infectious virus, bacterium or parasite. It usually is of acute onset, normally lasting less than 10 days and self-limiting. Sometimes it is referred to simply as 'gastro'. It is often refered to as the stomach flu even though it is not related to influenza. ==Aetiology== ===Viral causes=== The most common viral causes of acute gastroenteritis (AGE) in children <5 years of age in both developed nations as well as developing countries are rotavirus (up to 50% of the cases), noroviruses (the most common cause of outbreaks of AGE in all age groups), adenoviridae AD-40 and AD-41, astrovirus, and sapovirus. ===Bacterial causes=== This is less common in developed countries. ''Campylobacter jejuni'' is responsible for 5-10% of cases, whereas ''Salmonella'' species, ''Shigella'' species, and various pathogenic types of ''Escherichia coli'' account for a small percentage. In the third world enterotoxigenic, enteropathogenic and enteroinvasive ''Escherichia coli'' are important due to the sheer number of cases, whereas ''Shigella'' causes debilitating illness and has increasing resistance against cheap and readily available antibiotics. Cholera, caused by ''Vibrio cholerae'' is another important cause of acute diarrhoeal illness and subsequent death in the developing world. ===Parasites=== Outbreaks of ''Giardia lamblia'' can cause dehydrating diarrhoea in infants, and ''Cryptosporidium'' is known to cause 1-4% of cases of acute diarrhoea in hospitalised infants. ==Epidemiology== Globally, diarrhea caused 4.6 million deaths in children in 1980 alone, most of these in the third world. This number has now come down significantly to approximately 1.5 million deaths annually, largely due to global introduction of proper oral rehydration therapy (Victora et al 2000). The incidence in the developed nation is as high as 1-2.5 cases per child per year and a major cause of hospitalisation in this age group. ==Clinical features== The main symptoms include poor feeding in infants, vomiting and fever, usually rapidly followed by diarrhoea. Viral diarrhoea usually causes frequent watery stools, whereas blood stained diarrhoea may be indicative of bacterial colitis. The child with gastroenteritis may be lethargic and have signs of dehydration, dry mucous membranes, tachycardia, reduced skin turgor, sunken fontanelles and sunken eye balls, poor perfusion and ultimately shock. ==Differential diagnosis== It is important to consider infectious gastroenteritis as a diagnosis of exclusion. A few loose stools and vomiting may be the result of systemic infection such as pneumonia, septicaemia, urinary tract infection and even meningitis. Surgical conditions like appendicitis, intussusception and, rarely, even Hirschsprung's disease may mislead the clinician. ==Treatment== The main treatment of diarrhoeal illness in both children and adults is rehydration, i.e. replenishment of water lost in the stools. Depending on the degree of dehydration, this can be done orally with commercial or home-made rehydration fluids, or through vein delivery. ===Drug therapy=== Loperamide is an opioid analogue commonly used for symptomatic treatment of diarrhoea. It slows down gut motility, but does not cross the mature blood-brain barrier to cause the central nervous effect of other opioids. In too high doses, loperamide may cause constipation and significant slowing down of passage of faeces, but an appropriate single dose will not slow down the duration of the disease (Wingate et al, 2001). Loperamide is not recommended in children, especially in children younger than 2 years of age, as it may cause systemic toxicity due to an immature blood brain barrier, and oral rehydration therapy remains the main stay treatment for children. Antibiotics are of little or no use, unless persistent symptomatic colonisation (as seen in ''Giardia lamblia'' infestations) or septicaemia is present. ==Complications== Dehydration is the most concerning complication of the diarrhoea caused by gastroenteritis and needs prompt rectification by a clinician if severe. Febrile convulsions are not uncommon in children, especially with rotavirus infections. Sugar malabsorption is the most common complication, especially in infants. This may result in reappearance of diarrhoea once milk, and hence the sugar lactose, is reintroduced into the diet. ==References== Victora, C. G., Bryce, J., Fontaine, O., & Monasch, R. 2000, 'Reducing deaths from diarrhoea through oral rehydration therapy', ''Bulletin of The World Health Organization'', vol. 78, no. 10, pp. 1246-1255. Wingate D. et al. 2001. 'Guidelines for adults on self-medication for the treatment of acute diarrhoea', ''Alimentary Pharmacology & Therapeutics'', vol. 15, no. 6, pp. 773-782. ==External links== * [http://www.who.int/health_topics/diarrhoea/en/ The World Health Organisation on diarrhoea] * [http://www.emedicinehealth.com/articles/5962-1.asp eMedicine Health] Gastroenterology
Gastroenteritis
IIRC: * the present gastroenteritis article describes infectious gastroenteritis, which is a class of diseases, but * gastroenteritis is a symptom (not a disease) whose causes can include ingestion of irritants like ethyl alcohol, aspirin, and cooking spices (and perhaps also overeating?). IMO someone willing to do more research than i am at the moment should confirm this, rename, and convert the redir to a Dab between infectious gastroenteritis and something else ( non-infectious gastroenteritis is probably ''not'' what we need).
--User:JerzyUser talk:Jerzy 06:33, 2005 Feb 24 (UTC)
See other meanings of words starting from letter:
G
GA | GB | GC | GD | GE | GF | GH | GI | GJ | GK | GL | GM | GN | GO | GP | GR | GS | GT | GU | GW | GX | GY | GZ |Words begining with Gastroenteritis:
Gastroenteritis
Gastroenteritis
Gastroenteritis,_infectious
Gastroenteritis,_noninfectious,_unspec.
Gastroenteritis,_viral
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