Cytokines are small protein molecules that are the core of communication between immune system cells, and even between these cells and cells belonging to other biological tissue types. They are actively secreted by immune cells as well as other cell types. Cytokines that are produced by immune cells form a subset known as lymphokines. Their action is often local, but sometimes can have effects on the whole body. The first lymphokines were identified in the mid-1960's, with the best known being migration inhibition factor (MIF), simultaneously discovered by John David and Barry Bloom. The first cytokines were identified in cultures of kidney cells, by Stanley Cohen and his colleagues, in 1974. There are a lot of known cytokines that have both stimulating and suppressing action on lymphocyte cells and immune response. Some of the better known cytokines include: histamine, prostaglandin, tumor necrosis factor, IL-1, and IL-6. There are three classes of cytokines. Cytokines act by binding to their cell-specific receptor (biochemistry). These receptors are located in the cell membrane and each allows a distinct signal transduction cascade to start in the cell, that eventually will lead to biochemical and phenotypical changes in the target cell. Typically, receptors for cytokines are also tyrosine kinases. Some studies have shown links between cytokine levels and clinical depression [http://www.mcmaster.ca/inabis98/anisman/yirmiya0194/two.html]. == See also == * Adipokines * Chemokines * Interleukins * Interferon * Granulocyte-colony stimulating factor * Tumor necrosis factor * ELISPOT ==external links== *http://www.copewithcytokines.de Cytokines Online Pathfinder Encyclopaedia Cytokines
"Cytokines act by binding to their well specific cytokine receptor". - Is this correct, or should ''well'' read ''cell'' (or ''wall'')?
S. If lymyphokines are a sub-set of cytokines, then how can the former be discovered in the 1960s, and the latter in the 1970s (according to the article)? :Uhh, the members may have been discovered before the terminology came in vogue. Do you have any historical pointers? User:Jfdwolff | User_talk:Jfdwolff 21:33, 16 Feb 2005 (UTC)
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Words begining with Cytokine:
Cytokine
Cytokine
Cytokines
Cytokines
Cytokinesis
Cytokine_release_syndrome
Cytokine
Cytokines are small protein molecules that are the core of communication between immune system cells, and even between these cells and cells belonging to other biological tissue types. They are actively secreted by immune cells as well as other cell types. Cytokines that are produced by immune cells form a subset known as lymphokines. Their action is often local, but sometimes can have effects on the whole body. The first lymphokines were identified in the mid-1960's, with the best known being migration inhibition factor (MIF), simultaneously discovered by John David and Barry Bloom. The first cytokines were identified in cultures of kidney cells, by Stanley Cohen and his colleagues, in 1974. There are a lot of known cytokines that have both stimulating and suppressing action on lymphocyte cells and immune response. Some of the better known cytokines include: histamine, prostaglandin, tumor necrosis factor, IL-1, and IL-6. There are three classes of cytokines. Cytokines act by binding to their cell-specific receptor (biochemistry). These receptors are located in the cell membrane and each allows a distinct signal transduction cascade to start in the cell, that eventually will lead to biochemical and phenotypical changes in the target cell. Typically, receptors for cytokines are also tyrosine kinases. Some studies have shown links between cytokine levels and clinical depression [http://www.mcmaster.ca/inabis98/anisman/yirmiya0194/two.html]. == See also == * Adipokines * Chemokines * Interleukins * Interferon * Granulocyte-colony stimulating factor * Tumor necrosis factor * ELISPOT ==external links== *http://www.copewithcytokines.de Cytokines Online Pathfinder Encyclopaedia Cytokines
Cytokine
"Cytokines act by binding to their well specific cytokine receptor". - Is this correct, or should ''well'' read ''cell'' (or ''wall'')?
S. If lymyphokines are a sub-set of cytokines, then how can the former be discovered in the 1960s, and the latter in the 1970s (according to the article)? :Uhh, the members may have been discovered before the terminology came in vogue. Do you have any historical pointers? User:Jfdwolff | User_talk:Jfdwolff 21:33, 16 Feb 2005 (UTC)
See other meanings of words starting from letter:
C
CA | CB | CD | CE | CF | CG | CH | CI | CJ | CK | CL | CM | CN | CO | CP | CR | CS | CT | CU | CW | CX | CY | CZ |Words begining with Cytokine:
Cytokine
Cytokine
Cytokines
Cytokines
Cytokinesis
Cytokine_release_syndrome
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