Aldosterone is a steroid hormone synthesized from cholesterol by the enzyme aldosterone synthase. It is formed in the outer-section (zona glomerulosa) of the adrenal cortex of the adrenal gland, as the cells of other sections don't have the corresponding enzyme. It is the sole endogenous member of the class of mineralocorticoids. It helps regulate the body's electrolyte balance by acting on the mineralocorticoid receptor (MR). It diminishes the secretion of sodium (Na+) ions and therefore of water and stimulates the secretion of potassium (K+) ions through the kidneys. Unlike neuroreceptors, classic steroid receptors are located inside of cell (biology)s. The aldosterone/MR receptor complex binds to the coresponding section of DNA called hormone response element that alters protein synthesis and the transcription (genetics) of messenger RNA, including serum and glucocorticoid-induced kinase, channel-inducing factor, K-ras2A, and three subunits of the epithelial sodium channel. These genes are important for transepithelial sodium transport. Aldosterone is synthesized in reaction to increases of angiotensin II or blood plasma potassium, which are present in proportion to sodium deficiencies. It is also synthesized in response to different cytokines that get secreted due to hyperthermia. The secretion of aldosterone has a diurnal rhythm, with about 75% of the daily production is secreted between 04:00 and 10:00 each day. ==Aldosterone and the kidney== ===Control of aldosterone release=== *The role of baroreceptors *The role of the juxtaglomerular apparatus *The role of sympathetic nerves *The role of the renin-angiotensin system ==References== 1. Williams JS, Williams GH. ''50th anniversary of aldosterone.'' J Clin Endocrinol Metab. 2003 Jun;88(6):2364-72. [http://jcem.endojournals.org/cgi/content/full/88/6/2364 Full text]. PMID 12788829. Mineralocorticoids
i have too much :Conn's syndrome? User:Jfdwolff | User_talk:Jfdwolff 02:24, 10 Mar 2005 (UTC)
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Words begining with Aldosterone:
Aldosterone
Aldosterone
Aldosterone
Aldosterone is a steroid hormone synthesized from cholesterol by the enzyme aldosterone synthase. It is formed in the outer-section (zona glomerulosa) of the adrenal cortex of the adrenal gland, as the cells of other sections don't have the corresponding enzyme. It is the sole endogenous member of the class of mineralocorticoids. It helps regulate the body's electrolyte balance by acting on the mineralocorticoid receptor (MR). It diminishes the secretion of sodium (Na+) ions and therefore of water and stimulates the secretion of potassium (K+) ions through the kidneys. Unlike neuroreceptors, classic steroid receptors are located inside of cell (biology)s. The aldosterone/MR receptor complex binds to the coresponding section of DNA called hormone response element that alters protein synthesis and the transcription (genetics) of messenger RNA, including serum and glucocorticoid-induced kinase, channel-inducing factor, K-ras2A, and three subunits of the epithelial sodium channel. These genes are important for transepithelial sodium transport. Aldosterone is synthesized in reaction to increases of angiotensin II or blood plasma potassium, which are present in proportion to sodium deficiencies. It is also synthesized in response to different cytokines that get secreted due to hyperthermia. The secretion of aldosterone has a diurnal rhythm, with about 75% of the daily production is secreted between 04:00 and 10:00 each day. ==Aldosterone and the kidney== ===Control of aldosterone release=== *The role of baroreceptors *The role of the juxtaglomerular apparatus *The role of sympathetic nerves *The role of the renin-angiotensin system ==References== 1. Williams JS, Williams GH. ''50th anniversary of aldosterone.'' J Clin Endocrinol Metab. 2003 Jun;88(6):2364-72. [http://jcem.endojournals.org/cgi/content/full/88/6/2364 Full text]. PMID 12788829. Mineralocorticoids
Aldosterone
i have too much :Conn's syndrome? User:Jfdwolff | User_talk:Jfdwolff 02:24, 10 Mar 2005 (UTC)
See other meanings of words starting from letter:
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AB | AC | AD | AE | AF | AG | AH | AI | AJ | AK | AL | AM | AN | AO | AP | AR | AS | AT | AU | AW | AX | AY | AZ |Words begining with Aldosterone:
Aldosterone
Aldosterone
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